二次元嫩B Campus Now Equipped with Naloxone, an Antidote for Opioid Overdose

Naloxone

鈥淭he opioid epidemic is the worst public health crisis in decades,鈥澛爏aid 二次元嫩B Professor of Nursing Joanne Costello.

Opioid overdoses  in 2015 and this deadly epidemic shows no signs of slowing down.

In 2015, the latest year for which statistics are available from the , more than 50,000 Americans died of a drug overdose. Sixty-three percent of those deaths involved opioids 鈥 a class of drugs known as painkillers. 

That same year Costello and Lynn Wachtel, director of College Health Services, led an effort to bring naloxone 鈥 an antidote that can reverse an opioid overdose 鈥 to 二次元嫩B鈥檚 campus.

鈥淲e recognized that it isn鈥檛 a matter of 鈥榠f鈥 an overdose could happen at 二次元嫩B but 鈥榳hen,鈥欌 said Costello. Rhode Island is ranked among the five states with the highest rate of deaths due to drug overdose, said the .鈥嬧赌嬧赌

Costello and Wachtel
二次元嫩B Professor of Nursing Joanne Costello and Family Nurse Practitioner Lynn Wachtel, director of College Health Services.

Costell鈥媜 and Wachtel invited the Naloxone and Overdose Prevention Education Program of Rhode Island to train campus police and health services staff in the use of naloxone.鈥

Today 二次元嫩B police carry naloxone kits in their cruisers; there is a kit at the Office of Security and Safety, at the Office of College Health Services, the Counseling Center and in each of the dorms.

鈥淲e want to get ahead of it,鈥 said Chief of Campus Police Fred Ghio. 鈥淪o far, we鈥檝e been extremely fortunate. We haven鈥檛 had any incidences of overdoses on campus.鈥

Wachtel explained that 鈥渙pioids are painkillers that act on receptors in the brain. With continued use, they desensitize the brain鈥檚 receptors and the user needs to take more and more of the drug to get the same effect.鈥

Overdose occurs when the person experiences a dramatic decrease in respiration, causing them to go into a deep, coma-like sleep.

Naloxone in nasal form, which 二次元嫩B has acquired, is administered by squirting half of the bottle in one nostril and half in the other. If naloxone is administered quickly enough, within five to six minutes, the person will immediately snap out of the coma and awaken.  

鈥淭he way naloxone works is that it floods the receptors in the brain, pushing the opiate off the receptors, but it only lasts about 20 or 30 minutes,鈥 said Wachtel. 鈥淚f the person is not taken to an emergency room, they could re-overdose when naloxone leaves those receptors. Without emergency intervention, the person may stop breathing altogether.鈥

One of the strongest opioids on the market is fentanyl. Fentanyl is between 50 and 100 times more potent than heroin and has been involved in more than 50 percent of opioid overdose deaths.

When heroin dealers discovered that fentanyl delivers heroin鈥檚 high at a fraction of the cost, the production of illicitly manufactured fentanyl began as a cheaper, more efficient way to cut heroin. However, when fentanyl (or a fentanyl analog) is mixed with heroin, cocaine or another drug, it is never mixed evenly and may contain a lethal dose. In fact, those who are purchasing an illicit drug may not know their drug is laced with fentanyl.鈥

Fentanyl
On the left, a lethal dose of heroin; on the right, a lethal dose鈥 of fentanyl. Photo courtesy of Bruce Tayler/NH State Police Forensic Lab.

Although half of all U.S. opioid overdose deaths involve fentanyl, , said Wachtel and Costello. The most common include: methadone, oxycodone (such as OxyContin, Percodan and Percocet) and hydrocodone (such as Vicodin).

The opioid epidemic began with the overprescribing of painkillers, said Wachtel. Contributing to the epidemic were pharmaceutical companies who marketed their opioid painkillers as safe and effective. This allowed the drugs to proliferate, leading not only to widespread painkiller misuse but also to the misuse of more dangerous opioids like heroin and illegally manufactured fentanyl.

鈥淧eople don鈥檛 just go out and say, 鈥業鈥檓 going to start using heroin today,鈥欌 she said. They may have started with a legitimate prescription for pain and developed a dependency. When their refills ended, they began buying the pills on the black market at $1 a pill. If their habit is 30 pills a day, it is cheaper and more sustainable to buy heroin at $6 a dose.

Among new heroin users, approximately three out of four report having abused prescription opioids prior to using heroin.

鈥淭hese are our brothers and sisters, our aunts and uncles. It鈥檚 actually even our grandmothers,鈥 said Costello. 鈥淎n elderly person may be suffering from back pain and is put on pain meds. A soldier is wounded or an athlete has a sports injury and is prescribed a painkiller. There are a lot of reasons why people become addicted to opioids.鈥 

Though Naloxone distribution and other harm-reduction programs are not the solution to the opioid epidemic, naloxone will help keep individuals alive so that they can work toward recovery.

A talk regarding the national opioid epidemic by Shannon Monnat, chair of the Lerner Center for Public Health Promotion at Syracuse University, will be held at 二次元嫩B on Friday, Oct. 27, from 10 a.m. to noon in Alger Hall, Room 110. This event is free and open to the public.鈥